TABLE 1.1Overview of the TOXNET Databases

DatabaseSponsoring AgenciesFactual or BibliographicSubject Content
CCRISNCIFactualResults of carcinogenicity, mutagenicity, tumor production, tumor inhibition studies
DARTNLM, NIEHS, FDA, EPABibliographicLiterature on teratology and many aspects of reproductive toxicology
EMICNLM, EPA, NIEHSBibliographicLiterature since 1991 published on substances tested for genotoxic activity
EMICBACKNLM, EPA, NIEHSBibliographicPre-1950 through 1991 literature on substances tested for genotoxic activity
ETICBACKNLMBibliographicTeratology literature from 1950–1989, continued by DART
GENE-TOXEPAFactualResults from expert review of scientific literature on chemicals tested for mutagenicity
HSDBNLM (previously ATSDR)FactualPeer-reviewed summaries of the toxicology of potentially hazardous substances
IRISEPAFactualEPA health risk and regulatory information, includes carcinogenic and noncarcinogenic risk assessment data
RTECSNIOSHFactualToxic effects including skin and eye irritation, carcinogenicity, mutagenicity, and reproductive consequences
TRIEPAFactualAnnual estimated releases of toxic chemicals to the environment

NOTE: ATSDR = Agency for Toxic Substances and Disease Registry; CCRIS = Chemical Carcinogenesis Research Information System; DART = Developmental and Reproductive Toxicology; EMIC = Environmental Mutagen Information Center; EMICBACK = EMIC Back File; EPA = Environmental Protection Agency; ETICBACK = Environmental Teratology Information Center Backfile; FDA = Food and Drug Administration; GENE-TOX = Genetic Toxicology Data Bank; HSDB = Hazardous Substances Data Bank; IRIS = Integrated Risk Information System; NCI = National Cancer Institute; NIEHS = National Institute of Environmental Health Sciences; NIOSH = National Institute for Occupational Safety and Health; RTECS = Registry of Toxic Effects of Chemical Substances; TRI = Toxic Chemical Release Inventory.

From: 1, Introduction

Cover of Internet Access to the National Library of Medicine's Toxicology and Environmental Health Databases
Internet Access to the National Library of Medicine's Toxicology and Environmental Health Databases.
Institute of Medicine (US) Committee on Internet Access to the National Library of Medicine's Toxicology and Environmental Health Databases; Liverman CT, Fulco CE, Kipen HM, editors.
Washington (DC): National Academies Press (US); 1998.
Copyright © 1998, National Academy of Sciences.

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