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Cover of Safety of Silicone Breast Implants

Safety of Silicone Breast Implants

; Editors: Stuart Bondurant, Virginia Ernster, and Roger Herdman.

Washington (DC): National Academies Press (US); .
ISBN-10: 0-309-06532-1


This report is a general review of past and ongoing research on silicone breast implants, including (1) what associations between breast implants and various diseases, if any, are suggested by existing experimental, clinical, and epidemiological studies; (2) the nature and relative strength of these associations, (3) the quality of the studies; (4) the existence of plausible biological mechanisms to explain suggested associations between breast implants and disease; (5) the uncertainties associated with these kinds of analyses; and (6) suggestions for future research to fill in critical gaps. This report covers breast implants with a silicone shell, whether smooth, modified, or coated, and a gel or saline filler; local and systemic complications and manifestations of disease; and effects on mammographic screening and diagnosis and on the offspring of patients with breasts implants.


Support for this study was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Task Order No. 36, Contract No. N01-OD-4-2139.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

Copyright © 2000, National Academy of Sciences.
Bookshelf ID: NBK44792PMID: 20669503DOI: 10.17226/9602


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