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Wilt TJ, Shaukat A, Shamliyan T, et al. Lactose Intolerance and Health. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Feb. (Evidence Reports/Technology Assessments, No. 192.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Lactose Intolerance and Health

Lactose Intolerance and Health.

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Appendix BSearch Strings

Q1

Database: Ovid MEDLINE(R)
Search Strategy:
1lactose intoleran*.mp. or exp Lactose Intolerance/(2726)
2milk intoleran*.mp. (286)
3lactose malabsor*.mp. (493)
4exp Lactase/or lactase deficien*.mp. (961)
5prevalen*.mp. or exp Prevalence/(325492)
6exp Population/or population.mp. (682952)
7exp Lactose Tolerance Test/(313)
84 or 1 or 3 or 7 or 2 (3490)
96 or 5 (914652)
108 and 9 (515)
11exp Cohort Studies/(694867)
1211 or 5 (980226)
138 and 12 (424)
14limit 13 to (english language and humans) (365)
15remove duplicates from 14 (362)

Q2

Database: Ovid MEDLINE(R)
Search Strategy:
1exp Lactose Intolerance/dh [Diet Therapy] (185)
2limit 1 to english language (131)
3exp epidemiologic studies/(1121620)
43 and 2 (12)
5(lactose restricted or lactose free).mp. (242)
6dairy exclusion.mp. (0)
7dairy free.mp. (9)
87 or 5 (251)
98 and 3 (36)
10limit 9 to english language (28)
114 or 10 (35)
Database: Ovid MEDLINE(R)
Search Strategy:
1exp lactose/df (9)
2hypolactas$.mp. (181)
3(lactose adj2 free).mp. [mp=title, original title, abstract, name of substance word, subject heading word] (273)
4(dairy adj2 free).mp. [mp=title, original title, abstract, name of substance word, subject heading word] (42)
5(dairy adj2 exclu$).mp. (12)
6low lactose.mp. (123)
7limited lactose.mp. (2)
8(lactose adj2 restrict$).mp. (38)
9(dairy adj2 restrict$).mp. (19)
10exp Lactose Intolerance/(2478)
111 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 (2902)
12exp Diet/(144995)
13dh.fs. (29635)
14diet$.mp. (372626)
1513 or 12 or 14 (405928)
1611 and 15 (933)
17exp Bone Density/(28018)
18exp “Bone and Bones”/(382334)
19exp Osteoporosis/(33396)
20exp Fractures, Bone/(108442)
21exp Bone Diseases/(318865)
2221 or 18 or 19 or 17 or 20 (653576)
2322 and 16 (51)
24exp Treatment Outcome/(371740)
25“Outcome and Process Assessment (Health Care)”/(16843)
26outcome$.mp. (801020)
2725 or 24 or 26 (813119)
2827 and 16 (45)
29ep.fs. (828160)
30exp Epidemiologic Studies/(1087836)
31exp Epidemiologic Methods/(2978476)
3230 or 31 or 29 (3265926)
3332 and 16 (290)
3433 or 28 or 23 (341)
35limit 34 to (english language and humans) (298)
36limit 35 to journal article (293)
37limit 35 to (case reports or comment or editorial or letter or “review”) (66)
3836 not 37 (232)

MEDLINE® via Pubmed

Search “Diet, Vegetarian”[Mesh] AND calcium Limits: Humans, Journal Article, English158
Search “Diet, Vegetarian”[Mesh] AND relative risk AND dairy Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years20
Search “Diet, Vegetarian”[Mesh] AND relative risk Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years279
Search “Diet, Vegetarian”[Mesh] AND lactose Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years4
Search “Diet, Vegetarian”[Mesh] AND lactose free Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years0
Search “Diet, Vegetarian”[Mesh] AND cancer Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years156
Search “Diet, Vegetarian”[Mesh] AND bone Limits: Humans, Journal Article, English, All Adult: 19+ years, Preschool Child: 2–5 years, Child: 6–12 years, Adolescent: 13–18 years46
Search avoidance AND “Calcium, Dietary”[Mesh] AND “Dairy Products”[Mesh] Limits: Humans, Journal Article, English8
Search intolerance AND “Calcium, Dietary”[Mesh] AND “Dairy Products”[Mesh] Limits: Humans, Journal Article, English35
Search “Calcium, Dietary”[Mesh] AND “Dairy Products”[Mesh] Limits: Humans, Journal Article, English517
Search “Calcium, Dietary”[Mesh] AND relative risk AND lactose intolerance Limits: Humans, Journal Article, English22

Scirus

1–10 of 23 hits for “Lactose-free diet” (fracture)

Q3

Database: Ovid MEDLINE(R)
Search Strategy:
1exp epidemiologic studies/(1121620)
2exp lactose intolerance/(2583)
3exp Lactose Tolerance Test/(329)
43 and 2 (268)
51 and 4 (19)
6limit 5 to english language (18)
7exp lactose/ad (469)
87 and 2 (117)
98 and 1 (13)
10limit 9 to english language (13)
116 or 10 (27)
12lactose intake.mp. (63)
131 and 12 and 2 (8)
14limit 13 to english language (6)
1511 or 14 (30)

Q4

Database: Ovid MEDLINE(R)
Search Strategy:
1exp epidemiologic studies/(1121620)
2exp Lactose Intolerance/dh, su, dt, th [Diet Therapy, Surgery, Drug Therapy, Therapy] (413)
31 and 2 (20)
4limit 3 to english language (16)
5exp lactose intolerance/(2583)
6limit 5 to “therapy (optimized)” (114)
71 and 6 (11)
8limit 7 to english language (11)
94 or 8 (24)

MEDLINE® via Pubmed

“Probiotics”[Mesh] AND “lactose intolerance” Limits: Humans, Journal Article, English probiotics45
Search lactose-free AND “lactose intolerance” Limits: Humans, Journal Article, English55

Q5

Database: Ovid MEDLINE(R)
Search Strategy:
1exp Lactose Intolerance/(2583)
2td.fs. (203594)
31 and 2 (4)
4from 3 keep 1 (1)
5future research.mp. (21817)
6research need$.mp. (2549)
7trend$.mp. (147898)
81 and 5 (2)
96 and 1 (0)
101 and 7 (14)
118 or 4 or 10 (17)
12from 11 keep 1–2,11–13 (5)
13further investigation.mp. (26459)
141 and 13 (6)
15from 14 keep 2,4–5 (3)
1612 or 15 (7)
17understanding.mp. (243623)
181 and 17 (14)
19from 18 keep 1,3 (2)
20from 18 keep 1,3,6–11,13 (9)
2119 or 16 or 20 (16)

The broader preliminary literature search in MEDLINE® via Pubmed can be summarized as follows:

Relevant MeSH termsNumber identified
“Lactose Intolerance”[Mesh]2461
“Lactose Intolerance”[Mesh] NOT review NOT comment Limits: Humans, Journal Article, English1355
“Lactose Intolerance”[Mesh] AND “Epidemiologic Studies”[Mesh] Limits: Humans, English122
“Lactose Intolerance”[Mesh] Limits: Humans, Randomized Controlled Trial, English84

Additionally, the Cochrane Central Register of Controlled Trials (CENTRAL) was searched using the terms “lactose OR lactase”, which yielded 792 references.

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