Figure 1.9. Time course of glial scar formation at four time points as imaged by GFAP staining.

Figure 1.9

Time course of glial scar formation at four time points as imaged by GFAP staining. At 2- and 4-week time points, the astrocytic processes fall back into the void left by the probe extraction before tissue processing. By 6 weeks, the processes have interwoven to form a stronger, more dense sheath surrounding the implant. Minimal changes between the 6- and 12-week time points indicate the glial scar completion within 6 weeks. (Reprinted from Exp. Neurol., 156, 33–49, 1999. With permission from Elsevier.)

From: Chapter 1, Overview of Wound Healing in Different Tissue Types

Cover of Indwelling Neural Implants
Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment.
Reichert WM, editor.
Boca Raton (FL): CRC Press/Taylor & Francis; 2008.
Copyright © 2008, Taylor & Francis Group, LLC.

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