FIGURE 15.2. Bar graph depicting the number of OX-6 positive microglia in the striatum of rats following either sham of 6-hydroxydopamine (6-OHDA) lesions into the corpus striatum.

FIGURE 15.2

Bar graph depicting the number of OX-6 positive microglia in the striatum of rats following either sham of 6-hydroxydopamine (6-OHDA) lesions into the corpus striatum. This quantification of MHC class II receptors on microglia demonstrates that in rats treated with 6-OHDA and fed the control diet with normal levels of vitamins and minerals the inflammatory process continues to increase over the 4 weeks following the 6-OHDA insult. In rats that were fed the blueberry or spirulina diet prior to the insult, there was initially a much larger response to the 6-OHDA at 1 week; however, at 1 month following the insult, there was a significant reduction in the numbers of OX-6 positive microglia observed in the striatum. * = p < 0.05, p < 0.01, one-way ANOVA (see [143] for a full description).

From: Chapter 15, Oxidative Stress and the Aging Brain: From Theory to Prevention

Cover of Brain Aging
Brain Aging: Models, Methods, and Mechanisms.
Riddle DR, editor.
Boca Raton (FL): CRC Press/Taylor & Francis; 2007.
Copyright © 2007, Taylor & Francis Group, LLC.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.