The U.S. Department of State charged the Academies with the task of producing a protocol for development of standard operating procedures (SOPs) that would serve as a complement to the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and be included with the other materials in the 2010 toolkit. To accomplish this task, a committee with experience and knowledge in good chemical safety and security practices in academic and industrial laboratories with awareness of international standards and regulations was formed. The hope is that this toolkit expansion product will enhance the use of the previous reference book and the accompanying toolkit, especially in developing countries where safety resources are scarce and experience of operators and end-users may be limited.

Contents

• The National Academies of SCIENCES • ENGINEERING • MEDICINE
• COMMITTEE ON CHEMICAL MANAGEMENT TOOLKIT EXPANSION: STANDARD OPERATING PROCEDURES
• BOARD ON CHEMICAL SCIENCES AND TECHNOLOGY
• ACKNOWLEDGMENT OF REVIEWERS
• 1. STANDARD OPERATING PROCEDURES FOR CHEMICAL SAFETY
  • INTRODUCTION
  • WHAT IS A STANDARD OPERATING PROCEDURE
  • WHO IS RESPONSIBLE FOR DEVELOPING STANDARD OPERATING PROCEDURES
  • GUIDE TO DEVELOPING STANDARD OPERATING PROCEDURES
• 2. RISK ASSESSMENT FLOWCHART
  • INTRODUCTION
  • MANAGEMENT AND STORAGE
  • PROCESS RISK MITIGATION
• 3. CHEMICAL STORAGE MATRIX
  • INTRODUCTION
  • PRIMARY STORAGE REQUIREMENT
  • SECONDARY STORAGE REQUIREMENT
  • LABELING
  • INVENTORY OF CHEMICALS
• 4. STANDARD OPERATING PROCEDURE FORMS
  • INTRODUCTION
  • MODERATE RISK STANDARD OPERATING PROCEDURE
  • HIGH RISK STANDARD OPERATING PROCEDURE
• 5. APPLICATION OF THE GUIDE TO DEVELOPING STANDARD OPERATING PROCEDURES
  • SCENARIO 1: NEUTRALIZATION OF CARBONATE BY ACID
  • SCENARIO 2: USE AND FILTRATION OF A PYROPHORIC CATALYST
  • SCENARIO 3: TOXIC AND EXPLOSIVE GASES: HANDLING DIAZOMETHANE AND ALTERNATIVES
  • SCENARIO 4: REAGENT STORAGE
• 6. FORMS
  • RISK ASSESSMENT FLOWCHART
  • CHEMICAL STORAGE MATRIX
  • MODERATE RISK STANDARD OPERATING PROCEDURE FORM
  • MODERATE RISK STANDARD OPERATING PROCEDURE REVIEW AND MODIFICATIONS LOG
  • HIGH RISK STANDARD OPERATING PROCEDURE FORM
  • HIGH RISK STANDARD OPERATING PROCEDURE REVIEW AND MODIFICATIONS LOG
• APPENDIXES
  • A. CHARGE TO THE COMMITTEE
  • B. AVAILABLE RESOURCES
  • C. SEGREGATION LIST
  • D. FLAMMABLE LIST
  • E. SECURITY LIST
  • F. COMMITTEE AND STAFF BIOGRAPHIES

Suggested citation:

National Academies of Sciences, Engineering, and Medicine. (2016). Chemical Laboratory Safety and Security: A Guide to Developing Standard Operating Procedures. Committee on Chemical Management Toolkit Expansion: Standard Operating Procedures. Washington, DC: The National Academies Press. doi: 10.1726/21918.