Table E-2Demographic characteristics of included patients (Diagnosis review)

Author, YearNumber of PatientsMaleAgeAtopicSmoking StatusHistory of Asthma%predicted FEV1 (unless otherwise stated)Years of ExposureYears of SymptomsCurrent Medication Stopped for Testing
(%)mean (SD)(%)(%)(%)mean (SD)mean (SD)mean (SD)
Alvarez, 2001366.740.3 (13.6)0C: 0 - 94.7 (1.5) - 1.7 (0.6)No
Ex: 0
N: 100
Alvarez, 19962195.238.3 (15.7)42.9C: 14.3 - - - 5.5 (7.7)No
Anees, 200414173.846 (10.2)45.4C: 17.7 - - - - Yes
Ex: 33.3
N: 48.9
Avery, 196918 - - - - - - - - No
Balland, 19897561.3 - 24-52- - - -
Baur, 199822966.435.1 (11.4) - - - -8.6 (8.4) - No
Baur, 19797 - - - - - -4.8 (2.8) - -
Behr, 199070 - - - - - - - - No
Bernstein, 20025496.339.9 - - - -11.2 (11.1) - No
Biot, 198012 - 41.6 (11.4) - - - - - - -
Block, 1983710050 (13.6)85.7C: 42.9 - 101.7 (28.8)28.4 (16) - Yes
Ex: 42.9
N: 14.3
Burge, 19851593.345.7 (11.1)46.7C: 26.70- - - No
Ex: 40
N: 33.3
Burge, 1982b136 - - - - - - - - No
Burge, 198049 - - - - - - - - No
Burge, 1979a29 - - - - - - - - -
Burge, 1979b23 - - - - - - - - No
Burge, 19782114.345.2 (12.5)42.9C: 23.823.888.3 (16.5) - - No
Ex: 14.3
N: 66.7
Butcher, 198026 - - - - - - - - No
Carletti, 19973710041 (12)37.8C: 48.6 - - - - No
Cartier, 19896293.5 - 40.3C: 27.4 - 94 (22)8.8 (8.5) - -
Ex: 37.1
N: 35.5
Cartier, 198752038.8 (9.9)100-2090 (16.3)12.6 (4.3)0.7 (0.3)Yes
Cartier, 198654 - - - - - - - - No
Choudat, 19992195.229.6 (5.7) - - - 97 (12.3)11.6 (6.4) - No
Cirla, 197533 - - - - - 77 (7.8) - - No
Colas, 1985101004730-10-21.63.4No
Cortona, 198076 - 35 - - - - - - No
Cote, 199325100 - - - - - - - No
Coutts, 1984410038 (13) - - - - - - No
Curran, 1996201046.7 (11.4) - - - - - - -
Davison, 1983310029 (2.7)100C: 66.70PEF: 193.3 (135.8) - - No
Ex: 0
N: 33.3
DeZotti, 1996a47547.3 (12.3)50N: 100 - - - - -
DeZotti, 1996b5461.130.6 (9.6)25.9C: 24.144.4-8.7 (9.6) - No
Dellabianca, 19964047.535.6 (11.1)20C: 20 - - - 2.35 (10.6)-
Ex: 40
N: 42.5
Dente, 198642 - - - - - - - - -
DiFranco, 1998247545.3 (9.6)25C: 0 - - - 7.33 (4.5)Yes
Ex: 54.2
N: 45.8
DiStefano, 19992412.538.6 (8.8)37.5C: 29.212.575.8 (14.6) - - -
Ex: 16.7
N: 54.2
Duan, 19891833.3 - - -100-9.5 (4.8) - No
Ferguson, 19969063.334.3 (10.2) - C: 46.7 - -5.7 (5.9)1.92 (3.3)Yes
Ex: 35.6
N: 16.7
Gannon, 1996127 - - - - - - - - No
Girard, 20045257.740.4 (11.5)69.2C: 23.1 - -7.2 (8.1)10.65 (11.4)-
Ex: 44.2
N: 26.9
Graneek, 19879 - - - - - - - - -
Grosclaude, 19803073.338.710- - -101.9No
Harries, 19803745.937.5 (9.8)59.5- - - - - No
Hinojosa, 1986410040 (6.2)25C: 25 - -8.8 (3.3)4.8 (2.6)-
Ex: 25
N: 50
Howe, 19837041.1 (5)14.3C: 1000- - - No
Ex: 0
N: 0
Huggins, 200352 - - - - - - - - No
Jager, 19931414.334.7 (8.1)42.9-71.4- - - No
Karol, 1994637330.6 - - - -10.1 (9)3.08 (3.9)-
Kern, 19915119.637.9 (10.3)23.5C: 41.25.9- - - No
Ex: 13.7
N: 45.1
Keskinen, 1988358037 (10.5)31.4C: 34.3 - - - - No
Ex: 0
N: 65.7
Kim, 19991656.348.6 (10.4)37.5C: 6.3 - -20 (5) - No
Kim, 19978150.641.8 (8.1) - - - - - - No
Kongerud, 19921492.938.1 (9.7)28.6C: 50 - 94.9 (9.9) - - No
Ex: 14.3
N: 35.7
Kopferschmitt-Kubler, 19981190.936.1 (7.3)54.5C: 18.29.1FEV1: 3.4 (0.5) - - -
Ex: 54.5
N: 27.3
Koskela, 20033735.142.8 (8.3) - C: 13.5 - - - - Yes
Krakowiak, 200325 - 41.9 (11.6)72C: 2016FEV1: 3.9 (0.4)13 (7) - No
Ex: 12
N: 68
Lam, 197986 - 41.4 (10.5)23.3C: 7 - - - - No
Ex: 18.6
N: 74.4
LaPaglia, 1986309 - 55.6 (10.1) - -5.2-32.8 (10.5) - No
Larbanois, 200317462.638.4 (10)58N: 59.8 - - - 3.41 (4.5)Yes
Lemiere, 20013190.342.1 (13)71C: 58.1 - - - 3.35 (4.9)No
Ex: 0
N: 41.9
Liss, 199150724456- - -123.5No
Lozewicz, 1985742.943 (11)42.9C: 14.3 - - - - No
Malo, 1993a7491.9 - - C: 13.5 - 91 (18)9.4 (8.1) - Yes
Ex: 41.9
N: 44.6
Malo, 199116277.239.6 (11.8)54.3C: 30.2 - 92.7 (16.4)6.5 (8.8)1.9 (2.7)Yes
Ex: 40.7
N: 27.2
Malo, 199016476.238.8 (12.2)57.3C: 27.4 - -8.8 (8.4)3.15 (3.4)No
Ex: 34.8
N: 37.8
Malo, 1988a514937 (10)39.2N: 497.8-10 (8) - No
Mapp, 1986666.731.7 (13)33.3C: 16.7 - 104 (20.6)11.6 (10)2.11 (2.3)No
Ex: 33.3
N: 50
Mapp, 19791586.736.8 (12.2) - C: 6.7 - FEV1: 3.6 (0.7)7 - No
Ex: 13.3
N: 80
Merget, 19973476.526 (10.5) - - - -7.7 (8.4) - -
Merget, 19965794.737 (10)49.1C: 54.4098 (14) - 5.25 (5.3)Yes
Ex: 17.5
N: 10.5
Merget, 199342 - - 38.1C: 35.7 - -9.5 (8.5) - No
Ex: 42.9
N: 21.4
Mole, 19774010034.6 (6) - C: 37.5 - - - - No
Moller, 19861283.341.1 (14.6)16.7C: 2516.7-2.1 (3) - Yes
Ex: 25
N: 50
Moller, 19857 - - 28.6-28.6- - - No
Moscato, 19937585.340.1 (10.5)41.3C: 29.3 - -19.5 (31.8)4.2 (5.4)No
Ex: 26.7
N: 42.7
Munoz, 20048037 (7.3)37.5C: 37.5 - FEV1: 2.9 (0.7)11 (5.5) - No
Nielsen, 19885 - - - - - -13.8 (9.7) - No
Nordman, 19851225 - 16.7- - FEV1: 2.8 (0.7) - - No
O'Brien, 1979a24100 - - - - - - - No
O'Brien, 1979b63 - 43 (8.8)36.5C: 22.2 - - - - -
Ex: 23.8
N: 36.5
Obata, 19991710035.3 (10.6)70.6C: 0 - -6.2 (9.2)2.1 (2.7)Yes
Ex: 5.9
N: 94.1
Obtulowicz, 19984959.248.5 (8.3)36.7C: 46.9 - - - - Yes
Paggiaro, 1987b332 - 25.5 (12)36.1N: 67.8 - - - - No
Paggiaro, 198611475.446.2 (11.8)20.2C: 19.3 - - - 3.69 (3.5)No
Ex: 22.8
N: 57
Paggiaro, 1984b633.337.2 (11.7)50C: 50 - 95.5 (20.2)11.8 (4.4)5.7 (1.3)No
Ex: 0
N: 50
Paggiaro, 1984c - - - - - - - - - No
Paggiaro, 1981310049.3 (13.4)33.3C: 100 - 93.3 (14)3.3 (3.9)3.1 (4.1)Yes
Ex: 0
N: 0
Palczynski, 2003616.743.7 (7.9)16.7C: 0 - - - - No
Park, 2002b4 - 24.8 (1.3)75C: 0 - - - - No
Ex: 0
N: 100
Park, 20011368940.8 (8.7)38.2- - -9.2 (5.2) - No
Park, 1999637338.5 (10.6)52.4- - -5.7 (5.6) - No
Park, 199815100 - 93.3- - - - - No
Park, 1994410042 (13)75C: 0 - - - - No
Ex: 100
N: 0
Park, 199113 - - - - - - - - No
Park, 1989910035.6 (6)33.3C: 44.4 - FEV1: 3.5 (0.6)1.5 (0.5) - No
Ex: 55.6
N: 0
Perrin, 199023 - - - - - - - - -
Pezzini, 19842864.3 - 25- - -12.2 (8.5) - No
Prichard, 19842010032 - C: 45 - FEV1: 4 - - No
Ex: 15
N: 40
Quirce, 200058049.2 (9.5)60C: 0 - -23.8 (12.8)11.7 (5.9)No
Ex: 20
N: 80
Quirce, 199258040.8 (17.2)80C: 60 - 90 (8.2)22.2 (15.8)7.4 (5.6)No
Ex: 0
N: 40
Rasanen, 19942839.337.6 (9) - - - - - - Yes
Redlich, 19963 - - - - - - - - No
Ricciardi, 2003977.847.3 (10.6)11.1C: 11.1 - FEV1: 4.4 (0) - - No
Ex: 0
N: 88.9
Sander, 20017 - - - - - - - - No
Sastre, 20032281.838.6 (10.6)36.4C: 4.5 - -13.7 (9.1)3.7 (3.1)No
Ex: 9.1
N: 81.8
Schuermans, 200339 - - - - - - - - No
Schwaiblmair, 199755030.8 (14.1)14.5C: 34.5 - FEV1: 3 (0.7)15.1 (14.8)4.8 (5.2)No
Schwarting, 1979 - - - - - - - - - No
Shirai, 20032142.944 (14.5)52.4C: 14.3 - - - 3.17 (4.3)No
Ex: 33.3
N: 52.4
Shirakawa, 198812 - 48.3 (5.4)66.7C: 41.7 - - - - Yes
Slovak, 19812810041 (8.5)46.4C: 42.90- - - No
Ex: 32.1
N: 25
Symington, 1981837.5 - 25- - -8.1 (4) - No
Tabar, 2004102038.3 (10.2)60- - - - - No
Taivainen, 19941004744 (10.8) - C: 497- - - No
Ex: 28
N: 68
Tee, 199810193.1 - - - - - - - -
Tse, 198228 - - - - - - - - -
Vandenplas, 2001454.433.6 (6.1)68.9N: 73.320- - 3.01 (2.8)No
Vandenplas, 1995b13033 (4)53.8C: 15.4 - 97.4 (9.7) - 4 (3)Yes
Ex: 23.1
N: 61.5
Vanhanen, 20001136.436.5 (7.2)63.6C: 27.3 - 93.5 (8.2) - - -
Virtanen, 19961163.646 (7.3) - - - - - - No
Vogelmeier, 19911994.749.4 (2.5) - - - -6 (5.8) - No
Wurzinger, 199754039.6 (19.3) - - - - - - No
Zeiler, 2002966.740 (10)66.7C: 0 - - - - No
Ex: 44.4
N: 55.6
Zeiss, 19774 - 40.3 (13.4)25- - -2 (2.7) - No

Abbreviations: C = current; Ex = ex; FEV 1 = forced expiratory volume in one second; N = never; PEF = peak expiratory flow; SD = standard deviation

From: Appendix E: Evidence Tables

Cover of Diagnosis and Management of Work-Related Asthma
Diagnosis and Management of Work-Related Asthma.
Evidence Reports/Technology Assessments, No. 129.
Beach J, Rowe BH, Blitz S, et al.

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