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Eliminating the Public Health Problem of Hepatitis B and C in the United States

Phase One Report

Editors: Gillian J. Buckley and Brian L. Strom. Authors: ; ; ; .

Washington (DC): National Academies Press (US); .
ISBN-13: 978-0-309-43799-8ISBN-10: 0-309-43799-7

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide.

The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Contents

This activity was supported by Contract No. 10002774 with the US Department of Health and Human Services [Centers for Disease Control and Prevention]. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.

Suggested citation:

National Academies of Sciences, Engineering, and Medicine. 2016. Eliminating the public health problem of hepatitis B and C in the United States: Phase one report. Washington, DC: The National Academies Press. doi: 10.17226/23407.

Copyright 2016 by the National Academy of Sciences. All rights reserved.
Bookshelf ID: NBK368070PMID: 27336113DOI: 10.17226/23407

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