Zaher et al. 201393 G1: Propranolol oral, 2mg/kg/day in 2 daily doses (15) G2: Propranolol, topical, 1% ointment applied twice daily (15) G3: Propranolol, intralesional, 1mg injected weekly (15)
Quality: Fair | Age, mean±SD (range) G1+G2+G3: 8.82±4.6 (3–18)
G1: 9.13 (3–18) G2: 8.33 (1–18) G3: 9.0 (3–18)
Type NR | G1+G2+G3: multiple |
Grading system comparing photographic documentation; unblinded assessment Excellent: complete resolution achieved Good: sustained plateau with ≥ 50% reduction in size Fair: sustained plateau with < 50% reduction in size Poor: no response or worsening of IH
| Response to treatment, n (%) Excellent response G1: 9 (60) G2: 3 (20) G3: 2 (13.3)
Good response G1: 2 (13.3) G2: 5 (33.3) G3: 3 (20)
Fair G1: 1 (6.7) G2: 2 (13.3) G3: 3 (20)
Poor G1: 3 (20) G2: 5 (33.3) G3: 7 (46.7) | Rebound growth, n (%) G1: 1 (6.7) G2: 1 (6.7) G3: 2 (13.3) |