Excerpt

Digital breast tomosynthesis (DBT) has rapidly been adopted by many providers of mammography screening in the United States. This report summarizes the evidence published through October 2015 regarding the diagnostic test characteristics of tomosynthesis in screening populations.

Contents

• 1. Introduction
  • Purpose
  • Background
• 2. Methods
  • Key Question
  • Data Sources and Searches
  • Study Selection
  • Quality Assessment and Data Abstraction
• 3. Results
  • Literature Search
  • Summary of Results
• 4. Discussion
• References
• Appendix A Detailed Methods
• Appendix B Ongoing Studies and Trials Pending Assessment

Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services¹. Contract No. HHSA-290-2012-00015-I, Task Order No. 5. Prepared by: Center for Healthcare Policy and Research², Kaiser Permanente Research Affiliates Evidence-based Practice Center³

Suggested citation:

Melnikow J, Fenton JJ, Miglioretti D, Whitlock EP, Weyrich MS. Screening for Breast Cancer With Digital Breast Tomosynthesis. Evidence Synthesis No. 125. AHRQ Publication No. 14-05201-EF-2. Rockville, MD: Agency for Healthcare Research and Quality; 2016.

This report is based on research conducted by the University of California, Davis Center for Healthcare Policy and Research and the Kaiser Permanente Research Affiliates Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (HHSA-290-2012-00015-I, Task Order No. 5). The findings and conclusions in this document are those of the authors, who are responsible for its contents, and do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help health care decisionmakers—patients and clinicians, health system leaders, and policymakers, among others—make well-informed decisions and thereby improve the quality of health care services. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information (i.e., in the context of available resources and circumstances presented by individual patients).

This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

This document is in the public domain and may be used and reprinted without permission except those copyrighted materials that are clearly noted in the document. Further reproduction of those copyrighted materials is prohibited without the specific permission of copyright holders.

None of the investigators has any affiliations or financial involvement that conflicts with the material presented in this report.

1

5600 Fishers Lane, Rockville, MD 20857; www​.ahrq.gov

2

University of California, Davis, Sacramento, CA

3

Kaiser Permanente Center for Health Research, Portland, OR