Table 6Flexible sigmoidoscopy + Hemoccult SENSA strategies

Strategy
Test, Age Begin-Age Stop, Interval†
Outcomes per 1000 Persons
COLLYGΔCOLΔLYGΔCOL/ΔLYG‡
MISCAN
1FSIG+SENSA, 60–75, 20,31,817163---
2FSIG+SENSA, 60–75, 10,31,933171Near-efficient
3FSIG+SENSA, 60–75, 5,32,0311792131514.0
4FSIG+SENSA, 50–75, 20,32,658213Near-efficient
5FSIG+SENSA, 50–75, 10,32,756221Near-efficient
6FSIG+SENSA, 50–75, 5,32,8702308395216.3
7FSIG+SENSA, 50–85, 5,33,042233Near-efficient
8FSIG+SENSA, 50–75, 5,23,142235Near-efficient
9FSIG+SENSA, 50–85, 10, 23,245232Near-efficient
10FSIG+SENSA, 50–85, 5,23,321237Near-efficient
11FSIG+SENSA, 40–75, 5,33,5922497221938.8
12FSIG+SENSA, 40–85, 5,33,771251178367.1
13FSIG+SENSA, 40–75, 5,23,987253Near-efficient
14FSIG+SENSA, 40–85, 5,24,1542553844104.3
15FSIG+SENSA, 40–75, 10,14,568254Near-efficient
16FSIG+SENSA, 40–75, 5,14,625256Near-efficient
17FSIG+SENSA, 40–85, 5,14,7842566301454.8
SimCRC
1FSIG+SENSA, 60–75, 20,3956152---
2FSIG+SENSA, 60–75, 10,39991614494.7
3FSIG+SENSA, 60–75, 5,31,0451694585.5
4FSIG+SENSA, 50–75, 10,31,621246Near-efficient
5FSIG+SENSA, 50–75, 5,31,655257611887.0
6FSIG+SENSA, 40–75, 5,32,3343116785412.5
7FSIG+SENSA, 40–85, 5,32,619314Near-efficient
8FSIG+SENSA, 40–75, 10,22,817312Near-efficient
9FSIG+SENSA, 40–75, 5,22,824320490859.2
10FSIG+SENSA, 40–85, 5,23,1443223213120.0
11FSIG+SENSA, 40–85, 10,23,145316
12FSIG+SENSA, 40–75, 20,13,680322Near-efficient
13FSIG+SENSA, 40–75, 10,13,682324Near-efficient
14FSIG+SENSA, 40–75, 5,13,6843265404134.5
15FSIG+SENSA, 40–85, 20,14,018324Near-efficient
16FSIG+SENSA, 40–85, 10,14,018326Near-efficient
17FSIG+SENSA, 40–85, 5,14,0183283342168.7
*

COL = colonoscopy; FSIG = flexible sigmoidoscopy; LYG = life-years gained compared with no screening; SENSA = Hemoccult SENSA; ΔCOL = incremental number of colonoscopies compared with the next-best non-efficient strategy; ΔLYG = incremental number of life-years gained compared with the next-best nonefficient strategy. Bold indicates recommendable strategy

Age and intervals expressed as years.

Near-efficient strategies yield life-years gained within 98% of the efficient frontier.

From: Appendix 3: Results including starting at age 40 in efficient and near-efficient frontiers

Cover of Evaluating Test Strategies for Colorectal Cancer Screening—Age to Begin, Age to Stop, and Timing of Screening Intervals
Evaluating Test Strategies for Colorectal Cancer Screening—Age to Begin, Age to Stop, and Timing of Screening Intervals: A Decision Analysis of Colorectal Cancer Screening for the U.S. Preventive Services Task Force from the Cancer Intervention and Surveillance Modeling Network (CISNET) [Internet].
Evidence Syntheses, No. 65.2.
Zauber AG, Lansdorp-Vogelaar I, Knudsen AB, et al.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.