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Cover of Recognition and Alleviation of Pain in Laboratory Animals

Recognition and Alleviation of Pain in Laboratory Animals


Washington (DC): National Academies Press (US); .
ISBN-13: 978-0-309-12834-6ISBN-10: 0-309-12834-X


This report on the Recognition and Alleviation of Pain in Laboratory Animals was prepared to help scientists, veterinarians, research administrators, institutional animal care and use committees (IACUCs), and animal care staff understand the basis of animal pain, recognize and evaluate its presence and severity, and appreciate means to minimize or abolish pain, according to the charge to the committee that prepared this report: "The … report will update information based on the current scientific literature on recognizing and alleviating pain in laboratory animals. The report will discuss the physiology of pain in commonly used laboratory species. Specific emphasis will be placed on the identification of humane endpoints, pharmacologic and non-pharmacologic principles to control pain, and principles to utilize in minimizing pain associated with experimental procedures. As with the first report [on Distress], general guidelines and examples will be given to aid IACUC members, investigators and animal care staff in making decisions about protocols using laboratory animals under current federal regulations and policies."


This study was supported by the American Veterinary Medical Association; Aventis Pharmaceuticals; the Bosack-Kruger Foundation; Bristol-Myers Squibb; GlaxoSmithKline; Humane Society of the United States; Scientists Center for Animal Welfare; Wyeth-Ayerst Pharmaceuticals; Department of Agriculture, Animal and Plant Health Inspection Service; and Department of Health and Human Services, National Institutes of Health through Contract Number N01-OD-4-2139 Task Order #161.

Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of the organizations or agencies that provided support for the project. The content of this publication does not necessarily reflect the views or policies of the National Institutes of Health, nor does mention of trade names, commercial products, or organizations imply endorsement by the US government.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the Committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

Copyright © 2009, National Academy of Sciences.
Bookshelf ID: NBK32658PMID: 20662126DOI: 10.17226/12526


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