Table 211.1Drugs That Cause Fever

Most commonly
Amphotericin B
Antihistamines
Asparaginase
Barbiturates
Bleomycin sulfate
Methyldopa
Penicillin
Phenytoin sodium
Procainamide
Quinidine sulfate
Salicylates
Sulfonamides
Occasionally
Allopurinol
Azathioprine
Cephalosporins
Cimetidine
Cocaine derivatives
Hydralazine hydrochloride
Iodides
Isoniazid
Nitrofurantoin sodium
Para-aminosalicylic acid
Propylthiouracil
Rifampin
Streptokinase
Streptomycin sulfate
Vancomycin hydrochloride
Almost never
Digitalis
Chloramphenicol
Insulin
Tetracyclines

Source: Modified with permission of Lipsky BA, Hirshmann V. Drug fever. JAMA 1981;245:851–54.

From: Chapter 211, Fever, Chills, and Night Sweats

Cover of Clinical Methods
Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition.
Walker HK, Hall WD, Hurst JW, editors.
Boston: Butterworths; 1990.
Copyright © 1990, Butterworth Publishers, a division of Reed Publishing.

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