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Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001.

Cover of Endocrinology

Endocrinology: An Integrated Approach.

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Box 2.15Synthesis of insulin

Image ch2fb15.jpg

Image dclcc1.jpg Structure of the primary transcript of RNA

Image dclcc2.jpg Mature messenger (m) RNA after exicision of the introns

Image dclcc3.jpg Structure of proinsulin after cleavage of the signal sequence from pre-proinsulin

Image dclcc4.jpg Cleavage of the C peptide leaving biologically active insulin

Image dclcc5.jpg Packaging of insulin and C-peptide in secretory granules for storage and release

From: Chapter 2, The endocrine pancreas

Copyright © 2001, BIOS Scientific Publishers Limited.

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