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Cover of Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria, 3rd edition

Geneva: World Health Organization; .
ISBN-13: 978-92-4-154912-7

Overview

Malaria case management, which consists of prompt diagnosis and effective treatment, remains a vital component of malaria control and elimination strategies. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on new evidence as well as a recommendation on the use of drugs to prevent malaria in high-risk groups.

The core principles underpinning this edition include: early diagnosis and prompt, effective treatment; rational use of antimalarial treatment to ensure that only confirmed malaria cases receive antimalarials; the use of combination therapy in preventing or delaying development of resistance; and appropriate weight-based dosing of antimalarials to ensure prolonged useful therapeutic life and an equal chance of being cured for all patients.

The Guidelines include recommendations on the diagnosis and treatment of uncomplicated and severe malaria by all species, including in special at-risk populations (such as young children, pregnant women, TB or HIV/AIDS patients and non-immune travellers) and situations (such as epidemics and humanitarian emergencies), and on the use of drugs to prevent malaria in groups at high risk. They aim:

  • to assist policy-makers to design and refine effective national treatment policies on the basis of the best available evidence;
  • to help hospital and clinical care providers to design and refine effective treatment protocols on the basis of the best available evidence;
  • to promote the use of safe, effective malaria treatment; and
  • to protect currently effective malaria treatment against the development of resistance.

The recommendations in the main document are brief. For those who wish to study the evidence base in more detail, a series of annexes are provided with references to the appropriate sections of the main document.

Contents

The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.

The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.

All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use.

Copyright © World Health Organization 2015.

All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: tni.ohw@sredrokoob).

Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution– should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index.html).

Bookshelf ID: NBK294440PMID: 26020088

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