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Rugge JB, Bougatsos C, Chou R. Screening for and Treatment of Thyroid Dysfunction: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 Oct. (Evidence Syntheses, No. 118.)

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Screening for and Treatment of Thyroid Dysfunction: An Evidence Review for the U.S. Preventive Services Task Force [Internet].

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Table 1Classification of Thyroid Dysfunction: Biochemical Definition

ConditionTSH LevelThyroid HormonesComments
Overt hyperthyroidism<0.1 mIU/L or undetectableElevated T4 or T3
Overt hypothyroidism>4.5 mIU/LLow T4
Subclinical hyperthyroidism<0.1 mIU/LNormal T4 and T3Clearly low serum TSH
0.1 to 0.4 mIU/LNormal T4 and T3Low but detectable
Subclinical hypothyroidism4.5 to 10 mIU/LNormal T4Mildly elevated TSH
≥10 mIU/LNormal T4Markedly elevated TSH

Source: Jameson 2008,19 Surks 20048

Abbreviations: T3=triiodothyronine; T4=thyroxine; TSH=thyroid-stimulating hormone.

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