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Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Table 5Dietary Goitrogens

Cassava, lima beans, linseed, sorghum, sweet potatoContain cyanogenic glucosides; they are metabolized to thiocyanates that compete with iodine for thyroidal uptake
Cruciferous vegetables: cabbage, kale, cauliflower, broccoli, turnips, rapeseedContains glucosinolates; metabolites compete with iodine for thyroidal uptake
Soy, milletFlavonoids impair thyroid peroxidase activity
Selenium deficiencyAccumulated peroxides may damage the thyroid, and deiodinase deficiency impairs thyroid hormone synthesis
Iron deficiencyReduces heme-dependent thyroperoxidase activity in the thyroid and may blunt the efficacy of iodine prophylaxis
Vitamin A deficiencyIncreases TSH stimulation and goiter through decreased vitamin A-mediated suppression of the pituitary TSHβ gene

From: The Iodine Deficiency Disorders

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