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Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell. 3rd edition. New York: Garland Science; 1994.

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Cover of Molecular Biology of the Cell

Molecular Biology of the Cell. 3rd edition.

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Figure 6-63. Two types of DNA branch migration observed in experiments in vitro.

Figure 6-63Two types of DNA branch migration observed in experiments in vitro

(A) Spontaneous branch migration is a back-and-forth, random-walk type of process, and it therefore makes little progress over long distances. (B) RecA-protein-directed branch migration proceeds at a uniform rate in one direction, and it may be driven by the polarized assembly of the RecA protein filament on a DNA single strand, which occurs in the direction indicated. In addition, special DNA helicases that catalyze protein-directed branch migration even more efficiently are involved in recombination.

From: Genetic Recombination

Copyright © 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D Watson.

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