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Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell. 3rd edition. New York: Garland Science; 1994.

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Cover of Molecular Biology of the Cell

Molecular Biology of the Cell. 3rd edition.

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Figure 8-15. The way histone H1 is thought to help pack adjacent nucleosomes together.

Figure 8-15The way histone H1 is thought to help pack adjacent nucleosomes together

The globular core of H1 binds to each nucleosome near the site where the DNA helix enters and leaves the histone octamer. When H1 is present on the nucleosomes, 166 nucleotide pairs of DNA are protected from micrococcal nuclease digestion, compared with 146 nucleotide pairs for nucleosomes lacking H1 (see Figure 8-10).

From: Chromosomal DNA and Its Packaging

Copyright © 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D Watson.

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