From: RNA Synthesis and RNA Processing
Copyright © 1994, Bruce Alberts, Dennis Bray, Julian
Lewis, Martin Raff, Keith Roberts, and James D Watson.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell. 3rd edition. New York: Garland Science; 1994.
Molecular Biology of the Cell. 3rd edition.
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Figure 8-58The two known classes of self-splicing intron sequences
The group I intron sequences bind a free G nucleotide to a specific site to initiate splicing (see Figure3-21), while the group II intron sequences use a specially reactive A nucleotide in the intron sequence itself for the same purpose. The two mechanisms have been drawn in a way that emphasizes their similarities. Both are normally aided by proteins that speed up the reaction, but the catalysis is nevertheless mediated by the RNA in the intron sequence. The mechanism used by group II intron sequences forms a lariat and resembles the pathway catalyzed by the spliceosome (compare to Figure 8-54). (After T.R. Cech, Cell 44:207-210, 1986. © Cell Press.)
- Figure 8-58, The two known classes of self-splicing intron sequences - Molecular...Figure 8-58, The two known classes of self-splicing intron sequences - Molecular Biology of the Cell
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