Table 4-1Composition of CNS Myelin and Brain

MyelinWhite matter
Substancea HumanBovineRatHumanBovineGray matter (human)Whole brain (rat)
Protein30.024.729.539.039.555.356.9
Lipid70.075.370.554.955.032.737.0
Cholesterol27.728.127.327.523.622.023.0
Cerebroside22.724.023.719.822.55.414.6
Sulfatide3.83.67.15.45.01.74.8
Total galactolipid27.529.331.526.428.67.321.3
Ethanolamine phosphatides15.617.416.714.913.622.719.8
Lecithin11.210.911.312.812.926.722.0
Sphingomyelin7.97.13.27.76.76.93.8
Phosphatidylserine4.86.57.07.911.48.77.2
Phosphatidylinositol0.60.81.20.90.92.72.4
Plasmalogensb 12.314.114.111.212.28.811.6
Total phospholipid43.143.044.045.946.369.557.6
a

Protein and lipid figures in percent dry weight; all others in percent total lipid weight.

b

Plasmalogens are primarily ethanolamine phosphatides.

From: Characteristic Composition of Myelin

Cover of Basic Neurochemistry
Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition.
Siegel GJ, Agranoff BW, Albers RW, et al., editors.
Philadelphia: Lippincott-Raven; 1999.
Copyright © 1999, American Society for Neurochemistry.

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