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Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Table 2Contraindications to Progestin-only Hormonal Contraceptives

Progestin-only contraception should not be used for women with the following conditions:
• Known or suspected pregnancy
• Unexplained vaginal bleeding
• Breast cancer
Progestin-only IUDs should not be initiated in the following conditions:
• Suspected uterine infection
• Cervical cancer
Caution should be used when prescribing progestin only pills in the following conditions:
• Concurrent medication that cause progestins to be metabolized more rapidly:
• anti-seizure medications: phenytoin, carbamazepine, primidone, phenylbutazone, felbamate, ozcarbazine and lamotrigine (lamotrigine levels decreased by progestins)
• antibiotics: rifampin/rifampicin
• ritonavir- boosted protease inhibitors
• Women who have undergone bariatric surgery may have difficulty with absorption.
*There is no evidence that progestin-only methods increase the risk of cardiovascular events in a fashion similar to the combined oral contraceptive pill. Even though there is no evidence that progestin-only contraceptives cause cardiovascular events, the product labeling might still list active cardiovascular disease (or history of disease) as a contraindication.

From: Contraception

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