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Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.

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Cover of Immunobiology

Immunobiology: The Immune System in Health and Disease. 5th edition.

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Figure 2.6. Bactericidal agents produced or released by phagocytes on the ingestion of microorganisms.

Figure 2.6Bactericidal agents produced or released by phagocytes on the ingestion of microorganisms

Most of these agents are made by both macrophages and neutrophils. Some of them are toxic; others, such as lactoferrin, work by binding essential nutrients and preventing their uptake by the bacteria. The same substances can be released by phagocytes interacting with large antibody-coated surfaces such as parasitic worms or host tissues. As these agents are also toxic to host cells, phagocyte activation can cause extensive tissue damage during an infection.

From: The front line of host defense

Copyright © 2001, Garland Science.

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