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Movie 5Follicle cell transient clone development

In the Drosophila ovary, two follicle stem cells (FSCs) reside in separate niches on opposite sides of the germarium. Daughters from each stem cell commingle and undergo several transient divisions to cover germline cysts. Despite these complexities, lineage analysis can be used to identify the stem cells and track clonally related cells over time. Here, the growth of a transient clone derived from the earliest non-stem cell daughter of the FSC lineage is shown. These transient clones can easily be distinguished from stem cell clones (movie 6) by the fact that the region containing labeled cells moves posteriorly with time and is soon lost.

From: Lineage analysis of stem cells

Cover of StemBook
StemBook [Internet].
Cambridge (MA): Harvard Stem Cell Institute; 2008-.
Copyright: © 2008 D.T. Fox, L.X. Morris, T. Nystul, and A.C. Spradling.

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