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Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002.

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Cover of Molecular Biology of the Cell

Molecular Biology of the Cell. 4th edition.

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Figure 21-87. Branching morphogenesis of the lung.

Figure 21-87Branching morphogenesis of the lung

(A) How FGF10 and Sonic hedgehog are thought to induce the growth and branching of the buds of the bronchial tree. Many other signal molecules, such as BMP4, are also expressed in this system, and the suggested branching mechanism is only one of several possibilities. (B) A cast of the adult human bronchial tree, prepared by injecting resin into the airways; resins of different colors have been injected into different branches of the tree. (B, from R. Warwick and P.L. Williams, Gray's Anatomy, 35th edn. Edinburgh: Longman, 1973.)

From: The Mouse

Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .


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