Figure 11-39. The principle of temporal summation.

Figure 11-39The principle of temporal summation

Each presynaptic action potential arriving at a synapse produces a small postsynaptic potential, or PSP (black lines). When successive action potentials arrive at the same synapse, each PSP produced adds to the tail of the preceding one to produce a larger combined PSP (green lines). The greater the frequency of incoming action potentials, the greater the size of the combined PSP.

From: Ion Channels and the Electrical Properties of Membranes

Cover of Molecular Biology of the Cell
Molecular Biology of the Cell. 4th edition.
Alberts B, Johnson A, Lewis J, et al.
New York: Garland Science; 2002.
Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .

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