Figure 13-43. A low-density lipoprotein (LDL) particle.

Figure 13-43A low-density lipoprotein (LDL) particle

Each spherical particle has a mass of 3 × 106 daltons. It contains a core of about 1500 cholesterol molecules esterified to long-chain fatty acids that is surrounded by a lipid monolayer composed of about 800 phospholipid and 500 unesterified cholesterol molecules. A single molecule of a 500,000-dalton protein organizes the particle and mediates the specific binding of LDL to cell-surface receptor proteins.

From: Transport into the Cell from the Plasma Membrane: Endocytosis

Cover of Molecular Biology of the Cell
Molecular Biology of the Cell. 4th edition.
Alberts B, Johnson A, Lewis J, et al.
New York: Garland Science; 2002.
Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .

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