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Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002.

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Molecular Biology of the Cell. 4th edition.

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Figure 20-31. The acrosome reaction that occurs when a mammalian sperm fertilizes an egg.

Figure 20-31The acrosome reaction that occurs when a mammalian sperm fertilizes an egg

In mice, a single glycoprotein in the zona pellucida, ZP3, is thought to be responsible for both binding the sperm and inducing the acrosome reaction. Note that a mammalian sperm interacts tangentially with the egg plasma membrane so that fusion occurs at the equator, rather than at the tip, of the sperm head. In mice, the zona pellucida is about 6 μm thick, and sperm cross it at a rate of about 1 μm/min.

From: Fertilization

Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .

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