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National Research Council (US) Committee for Capitalizing on Science, Technology, and Innovation: An Assessment of the Small Business Innovation Research Program; Wessner CW, editor. Venture Funding and the NIH SBIR Program. Washington (DC): National Academies Press (US); 2009.

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Venture Funding and the NIH SBIR Program.

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DVenture-funded Firms: Data from Hoover’s Small Business Database and VentureSource

CompanyVenture Capital (Thousands of Dollars)RoundsLast Round DateFirst Round DateStatusTicker SymbolLast Known DateAnnual Revenue (Millions of Dollars)Number of EmployeesProfit/Loss
Advanced Tissue Sciences, Inc.90,578.0311/2/20014/1/1996Out of business2003
Albion Instruments8,968.071/1/19906/1/1986Sold2000
Ambion, Inc.10,500.015/1/20035/1/2003Sold200613.6
Applied Immune Sciences, Inc.44,060.1111/1/199111/1/1984Sold1995
Applied Molecular Evolution, Inc.32,350.066/1/20003/1/1990Sold10.2
Aronex Pharmaceuticals, Inc.9,496.033/2/19997/1/1991Sold2001
Aviron (FKA: Vector Pharmaceuticals, Inc.)87,340.1411/1/20006/1/1992Sold
Argus Software, Inc.3,815.947/30/19991/1/1995Foreign
Aurora Biosciences Corporation18,720.0312/15/19963/7/1996Foreign
AcryMed, Inc.3,500.043/1/20034/1/1994n/a
Alexion Pharmaceuticals, Inc.5,800.0212/23/199411/12/1993NASDAQALXN1.6241(131.5)
Automatix, Inc.21,850.0712/1/19871/1/1980n/a
Aastrom Biosciences, Inc.36,384.9810/30/20028/18/1989NASDAQASTM0.7(17.6)
ABIOMED, Inc.35,800.013/27/20073/27/2007NASDAQAMMD50.7324
Adolor Corporation137,483.075/31/200111/1/1994NASDAQADLR15.9179(69.7)
Alkermes, Inc.12,384.3510/1/199210/1/1987NASDAQalks240.08309.9
Amylin Pharmaceuticals, Inc.84,200.099/20/200211/1/1987NASDAQAMLN510.91,550(218.9)
ARIAD Pharmaceuticals, Inc.56,075.035/20/20032/1/1991NASDAQARIA0.9108(61.9)
Aradigm Corporation139,454.093/7/200310/16/1992OTCARDM4.8103(13.0)
Altea Therapeutics54,546.946/15/200711/21/2002private
Amedica Corporation44,569.044/27/20071/28/2004privatefailed IPO20070.133(6.3)
Amnis Corporation18,750.033/27/20062/28/2000private3.537
Ancile Pharmaceuticals, Inc.30,365.0610/27/200211/4/1998private3.230
Artecel Sciences, Inc.4,135.225/29/200211/29/2000private0.11
Atherotech, Inc.21,399.941/31/20053/31/1999private
Avocet Medical, Inc.36,801.037/1/200110/1/1996private
BioCryst Pharmaceuticals, Inc.39,964.939/30/20078/1/1992NASDAQ6.252(43.6)
BioMarin Pharmaceutical, Inc.53,000.025/16/20011/1/1998NASDAQ84.2314(28.5)
BIOQUAL, Inc. (FKA: Diagnon Corporation)1,351.025/1/19837/1/1981private19.4150
Biosearch, Inc.1,800.0212/1/19834/1/1983private4.665
Biosym Technologies, Inc.5,168.034/1/199210/1/1986Sold
BioTransplant, Inc.9,561.036/30/200110/1/1995Out of business2003
Cambridge Neuroscience, Inc. (FKA: Synax, Inc.)35,879.096/21/19971/1/1986Sold
Cell Based Delivery, Inc.11,175.025/7/20023/7/2002Out of business
Centaur Pharmaceuticals, Inc.63,451.0711/2/200112/1/1992Out of business2002
Cephalon, Inc.40,037.882/25/199910/1/1987NASDAQCEPH18,641.12,895144.8
Chektec Corporation846.034/1/199312/1/1988Out of business
Clarus Medical LLC (Medilase, Inc.)27,548.9125/1/19971/6/1989private0.23
Clontech Laboratories, Inc.28,836.027/1/19987/1/1997private17.0175
CoCensys, Inc.24,071.091/7/19972/1/1989Sold
Cognetix, Inc.19,010.026/1/20068/1/2001Out of business
CompuCyte Corporation18,700.038/1/19994/1/1996private6.728
Conductus, Inc.45,699.963/27/20029/1/1987Sold
Control Delivery Systems, Inc. (AKA: CDS, Inc.)34,500.018/22/20008/22/2000Sold200517.226
COR Therapeutics, Inc.20,652.061/1/19983/16/1988Sold2002
Corixa Corporation157,581.166/10/200312/2/1994Sold2005
Cortex Pharmaceuticals, Inc.9,100.027/1/19895/1/1988AMEXCOR1.226(16.2)
Creative BioMolecules, Inc.23,284.0187/1/19955/1/1982NASDAQCRIS16.768(8.8)
Cryolife, Inc.3,057.036/1/19881/1/1986NYSECRY81.33630.4
Cryopharm Corporation30,346.0101/1/19941/1/1988private2.525
Cubist Pharmaceuticals, Inc.36,283.059/23/19989/1/1992NASDAQCBST194.8410(0.4)
CuraGen Corporation26,790.029/1/19993/1/1997NASDAQCRGN39.6666(59.8)
CytoLogix Corporation46,850.055/29/20021/1/1997private
Cytomation, Inc.14,293.026/8/20015/1/1997Sold
Cytyc Corporation (FKA: Generitech Corporation)35,154.945/1/19951/1/1987Sold2006608.01,500139.5
Dharmacon Research, Inc.5,700.018/23/20028/23/2002private10.1120
Digirad Corporation (FKA: Aurora Technologies)75,320.094/24/20025/30/1995NASDAQDRAD71.9601(6.3)
DiscoveRx Corporation, Ltd.28,406.052/20/20072/1/1999private3.340
Discovery Laboratories, Inc.13,211.026/20/200311/5/2002NASDAQ0.0160(46.3)
Displaytech, Inc.70,225.153/12/20064/11/2000IPO20023.247
Edenspace Systems Corporation5,250.014/23/20074/23/2007private0.710
EKOS Corporation85,900.486/27/200710/1/1996private9.599
Endocyte, Inc.60,700.243/23/20077/1/2001private3.340
Epicyte Pharmaceutical, Inc.22,200.044/16/20017/1/1996Sold2004
EpiGenesis Pharmaceuticals, Inc.35,956.243/7/200710/1/1997private
Epoch Biosciences (FKA:MicroProbe Corporation)30,030.2137/1/19933/1/1986Sold2004
EraGen Biosciences, Inc. (FKA: Sulfonics, Inc.)32,647.033/15/200710/6/2005private
Exogene Corporation7,115.157/1/199310/1/1988Sold1996
Fluorous Technologies, Inc. (AKA: FTI)3,650.025/23/20036/20/2000private2.015
Genaera Corporation (FKA: Magainin Pharmaceuticals)18,106.0510/1/19983/1/1988NASDAQGENR0.946(21.2)
Genaissance Pharmaceuticals, Inc.75,749.9411/4/20048/1/1998Sold2005
Genelabs Technologies, Inc.34,949.486/29/200610/1/1984NASDAQGNLB11.266(8.7)
GeneMedicine, Inc.8,900.027/13/199410/1/1992private14.9110
Genetic Therapy, Inc.13,989.087/1/19948/1/1988private1.015
GenPharm International, Inc.18,989.182/29/20002/29/2000Sold
Geron Corporation42,074.851/1/19967/10/1992NASDAQGERN3.390(31.4)
Gilead Sciences, Inc.32,060.068/1/19928/1/1987NASDAQGILD3,026.12,525(1,190.0)
Gliatech, Inc.32,596.176/1/19957/1/1988Sold2000
Hauser Chemical Research, Inc.1,893.0312/7/19904/1/1988Out of business
Hawaii Biotech, Inc.16,500.0512/26/20066/7/2002private5.165
Houston Biotechnology, Inc.3,240.025/1/198610/1/1985Sold
Hypres, Inc.39,841.02012/31/20027/1/1983private8.033
Icagen, Inc.96,700.772/1/200710/1/1995NASDAQICGN8.472(24.8)
Illumigen Biosciences, Inc.7,950.087/6/20075/1/2000private1.510
Illumina, Inc.36,567.0211/1/199911/30/1998NASDAQILMN184.527740.0
Immtech Pharmaceuticals, Inc. (FKA: Immtech International)2,509.032/14/199412/21/1992AMEXIMM4.327(11.3)
ImmuLogic Pharmaceutical Corporation29,844.052/22/19935/1/1987Out of business2002
Immunicon Corporation106,800.476/29/20057/1/1988NASDAQIMMC8.7107(24.0)
ImmunoGen, Inc.21,934.071/1/19896/1/1981NASDAQIMGN38.2192(19.0)
Immusol, Inc.23,500.029/24/20036/1/2001Sold
IntraTherapeutics, Inc. (FKA: Cardia Catheter Company)32,224.283/31/200010/7/1991Sold2001
Invitrogen Corporation15,000.016/20/19976/20/1997NASDAQ1,263.54,835(191.0)
Iomai Corporation80,570.0910/25/20061/1/1998NASDAQIOMI1.566(31.8)
Irvine Sensors Corporation2,650.036/10/200310/1/1997NASDAQIRSN30.8166(8.5)
Isis Pharmaceuticals17,490.068/11/19942/1/1989NASDAQISIS24.5258(45.9)
Isolab, Inc.2,744.026/28/19905/1/1987Foreign
ISTO Technologies, Inc.25,725.058/3/20073/1/2000private1.624
Kurzweil Applied Intelligence, Inc.26,122.1131/1/19935/1/1984private
Large Scale Biology Corp. (FKA: Biosource Genetics Corp)11,675.163/1/199812/1/1987private0.820
Laser Diagnostic Technology, Inc.13,310.9511/30/20011/1/1994Foreign
Laserscope24,045.489/1/19873/1/1983Sold2006
LeukoSite, Inc.32,613.187/1/19989/1/1994Sold1999
LifeSpan BioSciences, Inc.19,000.014/17/20014/17/2001private3.340
Linguagen Corporation20,212.045/23/200612/30/2003private
Lucent Medical Systems, Inc.6,700.029/25/19987/1/1997private0.57
Lynx Therapeutics, Inc.72,200.459/25/20032/15/1994Sold2007
Markwell Medical Institute, Inc.882.055/1/19876/1/1981Out of business
MediChem Research Inc.35,000.016/28/19996/28/1999private
Medinox, Inc.21,199.821/8/20026/15/1999private
MediSpectra, Inc.58,970.087/21/20066/1/19961.621
Meridian Instruments, Inc.3,557.0410/1/19935/1/1983Sold
Message Pharmaceuticals, Inc.11,142.584/14/20041/1/1998Out of business2004
MIICRO, Inc.6,840.049/26/200110/31/1997private1.620
MIDI2.08,2505/3/20045/19/2005private1.325
Moberg Medical, Inc. (AKA: Moberg Research, Inc.)5,473.864/1/19971/1/1992private
Molecular Dynamics, Inc.22,717.077/1/19949/1/1987Sold1998
Myogen, Inc.191,452.8610/13/200410/5/1998Sold2006
Nanosphere, Inc.80,130.155/16/20061/25/2000NASDAQNSPH1.150113.0
NeoGenesis, Inc.22,999.916/21/20011/9/2001Sold2005
Nereus Pharmaceuticals, Inc.127,345.688/9/20077/29/1998private9.329
NeuroControl Corporation22,800.091/4/20013/3/1994private
Neurocrine Biosciences, Inc.21,499.965/23/19969/25/1992NASDAQNBIX39.2588(107.2)
Neuron Therapeutics, Inc. (FKA: ICTUS Pharmaceuticals)28,717.0412/7/200110/1/1998private
NimbleGen Systems, Inc.73,250.581/2/20079/1/2000Sold
Nimbus Medical, Inc.9,635.137/1/19863/1/1988Sold1996
Octagen Corporation4,800.023/6/20004/1/1998private
Ontogen24,945.0510/13/20005/19/1992Out of business2003
Onyx Pharmaceuticals, Inc.70,200.265/9/20024/24/1992NASDAQ0.3125(92.7)
Organ Recovery Systems13,999.817/29/20041/20/2003private2.427
Orquest, Inc.42,814.8510/16/20016/8/1994Sold2003
Palatin Technologies45,700.031/30/200411/1/1996AMEXPTN14.485(27.8)
Panacos Pharmaceuticals, Inc.26,550.036/28/200711/4/2000NASDAQPANC0.332(38.1)
Perlan Therapeutics, Inc.5,227.0312/27/20016/4/1999private1.214
Pharmacopeia Drug Discovery, Inc.8,472.018/11/20058/11/2005NASDAQPCOP16.9150(27.8)
PharmaSonics, Inc.22,700.046/30/20022/1/1997Out of business
Pharmavene, Inc.13,044.036/1/19964/1/1993Sold
PHT Corporation (AKA: Personal Health Technologies Corp.)48,250.2610/18/200411/3/1999private8.480
Phylos, Inc.25,100.0111/30/200011/30/2000private1.718
Physical Optics Corporation3,337.048/1/19908/1/1987private30.0150
Physical Sciences, Inc.492.027/1/19955/9/1995private12.4150
Premier Laser Systems, Inc6,145.041/1/19974/1/1994Out of business
Progenics Pharmaceuticals, Inc.21,448.0212/27/200512/1/1995NASDAQPGNX69.9149(21.6)
Promega Corporation5,250.045/27/199310/1/1982private175.0850
PRP, Inc.384.021/1/19964/1/1996private6.8130
Proteome, Inc.8,100.0112/1/199912/1/1999private
Quantum Dot Corporation (AKA: Q Dot)39,150.038/10/20051/1/1999Sold2005
Quantum Magnetics, Inc.3,800.037/1/199710/15/1995Out of business
Replidyne, Inc.126,500.168/17/20052/21/2002NASDAQRDYN16.085(29.3)
Repligen Corporation12,234.035/1/198511/1/1981NASDAQRGEN14.145(0.9)
RiboGene, Inc. (FKA: Transgene)48,233.2152/1/19971/1/1990Sold1999
Sangamo Biosciences16,950.0312/31/20016/1/1996NASDAQSGMO7.962(17.9)
Sangart, Inc.50,353.024/4/200710/31/2004private7.335
Scios Nova, Inc.(F.K.A Scios Inc)California Biotechnology)5,425.016/1/19826/1/1982Sold
Secretech800.0210/1/19909/1/1989Out of business
Selective Genetics, Inc. (FKA: Prizm Pharmaceuticals, Inc.)56,867.01412/1/20036/12/1992private
Sepracor, Inc.16,892.082/22/19931/1/1984NASDAQSEPR1,196.5228184.6
Signal Pharmaceuticals, Inc.44,543.71012/1/19991/1/1993private48.5134
Spire Corporation3,750.031/1/198711/1/1979NASDAQSPIR20.1118(8.1)
Stratagene Cloning Systems1,873.0212/31/19924/1/1987Sold
Structural Bioinformatics, Inc.46,371.743/22/200011/1/1996Sold
Sunesis Pharmaceuticals, Inc. (FKA: Mosaic Pharmaceutical)163,338.185/30/20072/17/1998NASDAQSNSS13.7138
Synaptic Pharmaceutical Corporation (FKA:Neurogenetic Corp)89,772.279/5/20011/1/1987Sold
T Cell Sciences, Inc.3,634.0310/1/19894/1/1985Out of business
Targeted Genetics Corporation46,450.046/28/20076/1/1992NASDAQTGEN9.995(34.0)
TechniScan Medical Systems, Inc.6,400.012/5/20072/5/2007private
Tegic Communications, Inc. (AKA:T9 Text Input)15,000.025/4/19991/22/1998Sold
Telefactor Corporation450.0312/31/199812/31/1997Sold2000
Telios Pharmaceuticals, Inc.30,530.071/1/19931/1/1986Sold
Third Wave Technologies, Inc.78,064.257/26/20006/30/1995NASDAQTWTI28.0154(18.9)
TraceDetect, Inc.1,600.0211/17/20033/15/2002private1.412
TransMolecular, Inc.42,364.342/20/20049/30/1997private1.218
Trimeris, Inc. (FKA: SL-1 Pharmaceuticals, Inc.)38,283.069/1/19992/12/1993NASDAQTRMS37.0907.4
United Biomedical, Inc.9,000.017/1/19977/1/1997private13.8285
UroCor, Inc. (FKA: CytoDiagnostics, Inc.)16,600.157/1/19957/1/1987Sold
VaxGen, Inc.29,449.023/1/19974/10/1996private
Vertex Pharmaceuticals, Inc.13,538.0510/1/19961/1/1989NASDAQTRTX216.4320(206.9)
VueSonix Sensors4,600.037/30/20046/9/2000private
Xeotron Corporation9,000.015/1/20015/1/2001Sold2004
Xeyex Corporation3,267.026/30/19991/1/1997Out of business
Zynaxis, Inc.(FKA: Zynaxis Cell Science/PKH Labs)37,581.081/1/19956/1/1988Out of business
Martek Biosciences Corporation35,167.181/1/19862/1/2005NASDAQMATK270.058214.9
Vestar, Inc.34,509.1157/1/19817/1/1993Out of business2000
Vical, Inc.17,850.076/1/19873/10/1993NASDAQVICL14.7155(23.1)

NOTE: Hoover’s data reflect current data available through Hoover’s Small Business Database as of September 2007.

SOURCES: Data on VC investments are from VentureSource; data on current and historical firms status are from Hoover’s Small Business Database (<http://www.hoovers.com>).

Copyright © 2009, National Academy of Sciences.
Bookshelf ID: NBK26466

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