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Barton S, Karner C, Salih F, et al. Clinical effectiveness of interventions for treatment-resistant anxiety in older people: a systematic review. Southampton (UK): NIHR Journals Library; 2014 Aug. (Health Technology Assessment, No. 18.50.)
Clinical effectiveness of interventions for treatment-resistant anxiety in older people: a systematic review.
Show detailsDSM-IV diagnostic criteria9,100 | ICD-10 diagnostic criteria11 |
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GAD | |
A. Excessive anxiety and worry (apprehensive expectation), occurring on more days than not for at least 6 months, about a number of events or activities (such as work or school performance) | A. A period of at least six months with prominent tension, worry and feelings of apprehension, about every-day events and problems |
B. The person finds it difficult to control the worry | B. At least four symptoms out of the following list of items must be present, of which at least one from items 1 to 4 Autonomic arousal symptoms
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C. The anxiety and worry are associated with three (or more) of the following six symptoms (with at least some symptoms present for more days than not for the past 6 months). Note that only one item is required in children
| C. The disorder does not meet the criteria for panic disorder, phobic anxiety disorders, obsessive–compulsive disorder or hypochondriacal disorder |
D. The focus of the anxiety and worry is not confined to features of an Axis I disorder, e.g. the anxiety or worry is not about having a panic attack (as in panic disorder), being embarrassed in public (as in social phobia), being contaminated (as in obsessive–compulsive disorder), being away from home or close relatives (as in separation anxiety disorder), gaining weight (as in anorexia nervosa), having multiple physical complaints (as in somatization disorder), or having a serious illness (as in hypochondriasis), and the anxiety and worry do not occur exclusively during PTSD | D. Most commonly used exclusion criteria: not sustained by a physical disorder, such as hyperthyroidism, an organic mental disorder or psychoactive substance-related disorder, such as excess consumption of amphetamine-like substances, or withdrawal from benzodiazepines |
E. The anxiety, worry or physical symptoms cause clinically significant distress or impairment in social, occupational or other important areas of functioning | |
F. The disturbance is not caused by the direct physiological effects of a substance (e.g. a drug of abuse, a medication) or a general medical condition (e.g. hyperthyroidism) and does not occur exclusively during a mood disorder, a psychotic disorder, or a pervasive developmental disorder | |
Obsessive–compulsive disorder | |
A. Either obsessions or compulsions: Obsessions as defined by (1), (2), (3) and (4):
| A. Either obsessions or compulsions (or both), present on most days for a period of at least 2 weeks |
B. At some point during the course of the disorder the person has recognised that the obsessions or compulsions are excessive or unreasonable. Note that this does not apply to children | B. Obsessions (thoughts, ideas or images) and compulsions (acts) share the following features, all of which must be present:
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C. The obsessions or compulsions cause marked distress, are time-consuming (take more than 1 hour a day, or significantly interfere with the person’s normal routine, occupational (or academic) functioning or usual social activities or relationships | C. The obsessions or compulsions cause distress or interfere with the subject’s social or individual functioning, usually by wasting time. |
D. If another Axis I disorder is present, the content of the obsessions or compulsions is not restricted to it (e.g. preoccupation with food in the presence of an eating disorder; hair pulling in the presence of trichotillomania; concern with appearance in the presence of body dysmorphic disorder; preoccupation with drugs in the presence of a substance use disorder; preoccupation with having a serious illness in the presence of hypochondriasis; preoccupation with sexual urges or fantasies in the presence of a paraphilia; or guilty ruminations in the presence of major depressive disorder) | D. Most commonly used exclusion criteria: not caused by other mental disorders, such as schizophrenia and related disorders, or mood (affective) disorders |
E. The disturbance is not caused by the direct physiological effects of a substance (e.g. a drug of abuse, a medication) or a general medical condition | |
Panic disordera | |
A. Both (1) and (2):
| A. Recurrent panic attacks that are not consistently associated with a specific situation or object and often occurring spontaneously (i.e. the episodes are unpredictable). The panic attacks are not associated with marked exertion or with exposure to dangerous or life-threatening situations |
B. Absence of agoraphobia/presence of agoraphobia | B. A panic attack is characterised by all of the following:
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C. The panic attacks are not caused by the direct physiological effects of a substance (e.g. a drug of abuse, a medication) or a general medical condition (e.g. hyperthyroidism) | C. Most commonly used exclusion criteria: not caused by a physical disorder, organic mental disorder, or other mental disorder such as schizophrenia and related disorders, affective disorders or somatoform disorders |
D. The panic attacks are not better accounted for by another mental disorder, such as social phobia (e.g. occurring on exposure to feared social situations), specific phobia (e.g. exposure to a specific phobic situation), OCD (e.g. on exposure to dirt in someone with an obsession about contamination), PTSD (e.g. in response to stimuli associated with a severe stressor) or separation anxiety disorder (e.g. in response to being away from home or close relatives) | |
PTSD | |
A. The person has been exposed to a traumatic event in which both of the following were present:
| A. Exposure to a stressful event or situation (either short or long lasting) of exceptionally threatening or catastrophic nature, which is likely to cause pervasive distress in almost anyone |
B. The traumatic event is persistently re-experienced in one (or more) of the following ways:
| B. Persistent remembering or ‘reliving’ the stressor by intrusive flash backs, vivid memories, recurring dreams or by experiencing distress when exposed to circumstances resembling or associated with the stressor |
C. Persistent avoidance of stimuli associated with the trauma and numbing of general responsiveness (not present before the trauma), as indicated by three (or more) of the following:
| C. Actual or preferred avoidance of circumstances resembling, or associated with, the stressor (not present before exposure to the stressor) |
D. Persistent symptoms of increased arousal (not present before the trauma), as indicated by two (or more) of the following:
| D. Either (1) or (2):
|
E. Duration of the disturbance (symptoms in Criteria B, C and D) is more than 1 month | E. Criteria B, C and D all occurred within six months of the stressful event or the end of a period of stress (for some purposes, onset delayed more than six months may be included but this should be clearly specified separately) |
F. The disturbance causes clinically significant distress or impairment in social, occupational or other important areas of functioning | |
Social anxiety disorder | |
A. A marked and persistent fear of one or more social or performance situations in which the person is exposed to unfamiliar people or to possible scrutiny by others. The individual fears that he or she will act in a way (or show anxiety symptoms) that will be humiliating or embarrassing. Note: in children, there must be evidence of the capacity for age-appropriate social relationships with familiar people and the anxiety must occur in peer settings, not just interactions with adults | A. Either (1) or (2):
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B. Exposure to the feared social situation almost invariably provokes anxiety, which may take the form of a situationally bound or situationally predisposed Panic attack. Note: in children, the anxiety may be expressed by crying, tantrums, freezing, or shrinking from social situations with unfamiliar people | B. At least two symptoms of anxiety in the feared situation at some time since the onset of the disorder, as defined in criterion B for agoraphobia and in addition one of the following symptoms:
|
C. The person recognises that the fear is excessive or unreasonable. Note: in children, this feature may be absent | C. Significant emotional distress caused by the symptoms or by the avoidance |
D. The feared social or performance situations are avoided or else are endured with intense anxiety or distress | D. Recognition that the symptoms or the avoidance are excessive or unreasonable |
E. The avoidance, anxious anticipation, or distress in the feared social or performance situation(s) interferes significantly with the person’s normal routine, occupational (academic) functioning, or social activities or relationships, or there is marked distress about having the phobia | E. Symptoms are restricted to, or predominate in, the feared situation or when thinking about it |
F. In individuals under age 18 years, the duration is at least 6 months | F. Most commonly used exclusion criteria: Criteria A and B are not caused by delusions, hallucinations or other symptoms of disorders such as organic mental disorders, schizophrenia and related disorders, affective disorders or OCD, and are not secondary to cultural beliefs |
G. The fear or avoidance is not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition and is not better accounted for by another mental disorder (e.g., panic disorder with or without agoraphobia, separation anxiety, body dysmorphic disorder, a pervasive developmental disorder, or schizoid personality disorder) | |
H. If a general medical condition or another mental disorder is present, the fear in Criterion A is unrelated to it, e.g. the fear is not of stuttering, trembling in Parkinson’s disease, or exhibiting abnormal eating behaviour in anorexia nervosa |
- a
The DSM-IV distinguishes panic disorder with agoraphobia from panic disorder without agoraphobia; as indicated by criterion B under the heading of panic disorder.
- Diagnostic criteria for anxiety disorders set out in DSM-IV and ICD-10 classific...Diagnostic criteria for anxiety disorders set out in DSM-IV and ICD-10 classification systems - Clinical effectiveness of interventions for treatment-resistant anxiety in older people: a systematic review
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