Box 4.10Clinical features of Cushing's syndrome

  • Common*
    • Moon face (with plethora) (~100%)
    • Weight gain, central obesity (~100%)
    • Hypertension (~80%)
    • Mental changes (~80%)
    • Impaired glucose tolerance/diabetes mellitus (~70%)
    • Hypogonadism - menstrual irregularity/infertility in women, loss of libido in men (~70%)
    • Hirsutism in women (~70%)
    • Purple striae (~60%)
    • Acne (~60%)
    • Osteopenia/osteoporosis (~50%)
    • Easy bruising (~50%)
    • Proximal myopathy (~50%)
  • Less common
    • Poor wound healing (~30%)
    • Polycythemia (~10%)
    • Renal stones (~10%)
    • Headache (~10%)
    • Exophthalmos (~10%)
*

Compare with the photographs in Box 4.3.

From: Chapter 4, The adrenal gland

Cover of Endocrinology
Endocrinology: An Integrated Approach.
Nussey S, Whitehead S.
Copyright © 2001, BIOS Scientific Publishers Limited.

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