FIGURE 22.4. Pairs of stimulus responses recorded simultaneously with voltammetric microelectrodes at the posterior site (a), adjacent to a microdialysis probe (b), and at the outlet of a microdialysis probe (c).

FIGURE 22.4

Pairs of stimulus responses recorded simultaneously with voltammetric microelectrodes at the posterior site (a), adjacent to a microdialysis probe (b), and at the outlet of a microdialysis probe (c). The experiment was initiated 2 h after implantation of the dialytrode at the anterior site. The responses were recorded before (pre) and 25 min after (post) systemic administration of nomifensine (20 mg/kg, i.p.). The open circles show the beginning and end of the stimulus. The vertical arrow in (c) indicates the time after the start of the stimulus the response was expected at the outlet electrode, based on the delay time measured during probe precalibration. The vertical scale bars were determined by post-calibration of each microelectrode.

From: Chapter 22, In Vivo Fast-Scan Cyclic Voltammetry of Dopamine near Microdialysis Probes

Cover of Electrochemical Methods for Neuroscience
Electrochemical Methods for Neuroscience.
Michael AC, Borland LM, editors.
Boca Raton (FL): CRC Press/Taylor & Francis; 2007.
Copyright © 2007, Taylor & Francis Group, LLC.

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