Chemical name:99mTc-N,N'-Bis(S-benzoyl-thioglycoloyl)diamidopropanoyl)-KRAS-PNA-d(Cys-Ser-Lys-Cys)
Image PNAKRAS99mTc.jpg
Abbreviated name:99mTc-WT4351
Synonym:99mTc-KRAS PNA-peptide chimera, 99mTc-SBTG2DAP-KRAS-PNA-d(CSKC)
Agent Category:Peptide
Target:IGF1 receptor (IGF1R), KRAS mRNA
Target Category:Binding to IGF1R, internalized, and hybridized to KRAS mRNA
Method of detection:Single-photon emission computed tomography (SPECT) and planar gamma imaging
Source of signal:99mTc
Activation:No
Studies:
  • Checkbox In vitro
  • Checkbox Rodents

99mTc-WT4351 structure. Tc represents 99mTc. The 99mTc coordination configuration has not been confirmed by experiments.
Click on protein, nucleotide (RefSeq), and gene for more information about IGF1.

From: 99mTc-N,N'-Bis(S-benzoyl-thioglycoloyl)diamidopropanoyl-KRAS-PNA-d(Cys-Ser-Lys-Cys)

Cover of Molecular Imaging and Contrast Agent Database (MICAD)
Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

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