Table 2Proteins involved in cell division of E. coli and their homologs identified in H. pylori strains 26695a and J99b

Homolog in H. pylori:
E. coli geneFunction26695J99
min genes
minCCell division inhibitor. Complex with MinD.
minDSeptum site-determining protein. Complex with MinC.03310314
minETopological specificity protein. Compete to MinCD. Form MinE ring.03320315
fts genes
ftsABridge between FtsZ and other division proteins.09780912
ftsEComplex with FtsX. Form ABC transporter for salt and division protein transport.07480685
ftsHAAA (ATPases associated with diverse (cellular activities) protease family.02860271
ftsHcATP-dependent zinc protease. AAA protease family.10690356
ftsIPenicillin-binding protein 3. Transpeptidase for septum formation.11561464
ftsKChromosome segregation and cell division. Septum formation.10900335
ftsLCytoplasmic membrane protein. Ring structure for septum formation.
ftsNCytoplasmic membrane protein. Assembly and stability of septation machinery.
ftsQCytoplasmic membrane protein. Involved in septum formation.
ftsWStability of Z ring. Peptidoglycan synthesis with Ftsl.15601468
ftsXComplex with FtsE. Form ABC transporter for salt and protein transport.07490686
ftsYSignal recognition particle receptor.07630700
ftsZFtsZ ring to initiate septum formation.09790913
Other genes
ficcAMP-induced cell filamentation.11591086
cdrAcSuppress cell division.00660061
a

Tomb et al. (64).

b

Alm et al. (2).

c

Genes identified also in H. pylori. (20, 62).

From: Chapter 23, Chromosomal Replication, Plasmid Replication, and Cell Division

Cover of Helicobacter pylori
Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
Copyright © 2001, ASM Press.

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