Table 135.3"Euthyroid Sick" Syndromea

FindingsMechanisms
Normal thyroid morphology
Severity of illness and mortality rate inversely related to T4 concentration
Chemical findingsTRH response decreased
 Low Total T4Decreased TBG
 Normal, low, high free T4b
 Low T3Decreased conversion of T4 to T3 and increased reverse T3 (medication: steroid, beta-blockade; starvation)
 Increased Reverse T3
 Low TBG
 Elevated T3 resin uptake
 Normal TSH
 Blunted response to TRHBlock to cellular uptake T4
a

Associated with acute and chronic illness.

b

Depends on method.

From: Chapter 135, Thyroid Disease

Cover of Clinical Methods
Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition.
Walker HK, Hall WD, Hurst JW, editors.
Boston: Butterworths; 1990.
Copyright © 1990, Butterworth Publishers, a division of Reed Publishing.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.