Figure 31.22. Structure of Two Nuclear Hormone Receptor Domains.

Figure 31.22Structure of Two Nuclear Hormone Receptor Domains

Figure 31.22. Structure of Two Nuclear Hormone Receptor Domains. Nuclear hormone receptors contain two crucial conserved domains: (1) a DNA-binding domain toward the center of the sequence and (2) a ligand-binding domain toward the carboxyl terminus. The structure of a dimer of the DNA-binding domain bound to DNA is shown, as is one monomer of the normally dimeric ligand-binding domain.

From: Section 31.3, Transcriptional Activation and Repression Are Mediated by Protein-Protein Interactions

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.