Figure 23.8. Biosynthesis of Thiamine.

Figure 23.8Biosynthesis of Thiamine

The biosynthesis of thiamine begins with the addition of sulfide to the carboxyl terminus of the protein ThiS. This protein is activated by adenylation and conjugated in a manner analogous to the first steps in the ubiquitin pathway.

From: Section 23.2, Protein Turnover Is Tightly Regulated

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

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