Figure 26.17. Endocytosis of LDL Bound to Its Receptor.

Figure 26.17Endocytosis of LDL Bound to Its Receptor

(A) Electron micrograph showing LDL (conjugated to ferritin for visualization, dark spots) bound to a coated-pit region on the surface of a cultured human fibroblast cell. (B) Micrograph showing this region invaginating and fusing to form an endocytic vesicle [From R. G. W. Anderson, M. S. Brown, and J. L. Goldstein. Cell 10 (1977): 351.]

From: Section 26.3, The Complex Regulation of Cholesterol Biosynthesis Takes Place at Several Levels

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

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