BOX 5-1 CA 15-3

The CA 15-3 protein is a member of the family of proteins known as mucins, whose normal function is cell protection and lubrication. It plays a role in reducing cell adhesion and is found throughout the body. Elevated levels in breast cancer tissue may be involved in metastasis. CA 15-3 levels can also be elevated in patients with other cancers (lung, colorectal, ovarian, pancreatic) or because of hepatitis or cirrhosis of the liver.

From: 5, Biologically Based Technologies

Cover of Saving Women's Lives
Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis.
Institute of Medicine (US) and National Research Council (US) Committee on New Approaches to Early Detection and Diagnosis of Breast Cancer; Joy JE, Penhoet EE, Petitti DB, editors.
Washington (DC): National Academies Press (US); 2005.
Copyright © 2005, National Academy of Sciences.

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