Figure 16-30. Repair of AP (apurinic or apyrimidinic) sites.

Figure 16-30

Repair of AP (apurinic or apyrimidinic) sites. AP endonucleases recognize AP sites and cut the phosphodiester bond. A stretch of DNA is removed by an exonuclease, and the resulting gap is filled by DNA polymerase I and DNA ligase. (After B. Lewin, Genes. Copyright © 1983 by John Wiley.)

From: Biological repair mechanisms

Cover of An Introduction to Genetic Analysis
An Introduction to Genetic Analysis. 7th edition.
Griffiths AJF, Miller JH, Suzuki DT, et al.
New York: W. H. Freeman; 2000.
Copyright © 2000, W. H. Freeman and Company.

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