Figure 12-5. Consensus sequence of the minimal bacterial replication origin based on analyses of genomes from six bacterial species.

Figure 12-5Consensus sequence of the minimal bacterial replication origin based on analyses of genomes from six bacterial species

Similar sequences constitute each origin; the 13-bp repetitive sequences (orange) are rich in adenine and thymine residues. The 9-bp repetitive sequences (brown) exist in both orientations; that is, the lower-right sequence, read right to left, is the same as that of the upper-left sequence, read left to right. These sequences are referred to as 13-mers and 9-mers, respectively. Indicated nucleotide position numbers are arbitrary. [See J. Zyskind et al., 1983, Proc. Nat’l. Acad. Sci. USA 80:1164.]

From: Section 12.1, General Features of Chromosomal Replication

Cover of Molecular Cell Biology
Molecular Cell Biology. 4th edition.
Lodish H, Berk A, Zipursky SL, et al.
New York: W. H. Freeman; 2000.
Copyright © 2000, W. H. Freeman and Company.

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