Figure 7.13. Gene inactivation by homologous recombination.

Figure 7.13Gene inactivation by homologous recombination

The chromosomal copy of the target gene recombines with a disrupted version of the gene carried by a cloning vector. As a result, the target gene becomes inactivated. For more information on recombination see Section 14.3.

From: Chapter 7, Understanding a Genome Sequence

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

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