Figure 12.24. The postulated role of the anchor cell in determining cell fate during vulva development in Caenorhabditis elegans.

Figure 12.24The postulated role of the anchor cell in determining cell fate during vulva development in Caenorhabditis elegans

It is thought that release of the signaling compound LIN-3 by the anchor cell commits P6.p (shown in blue), the cell closest to the anchor cell, to the primary vulva cell fate. P5.p and P7.p (shown in green) are further away from the anchor cell and so are exposed to a lower concentration of LIN-3 and become secondary vulva cells. As described in the text, there is evidence that commitment of the secondary cells to their fates is also influenced by signals from the primary vulva cell.

From: Chapter 12, Regulation of Genome Activity

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

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