Figure 13.9. Structure of a yeast origin of replication.

Figure 13.9Structure of a yeast origin of replication

(A) Structure of ARS1, a typical autonomously replicating sequence (ARS) that acts as an origin of replication in Saccharomyces cerevisiae. The relative positions of the functional sequences A, B1, B2 and B3 are shown. For more details see Bielinsky and Gerbi (1998). (B) Melting of the helix occurs within subdomain B2, induced by attachment of the ARS binding protein 1 (ABF1) to subdomain B3. The proteins of the origin replication complex (ORC) are permanently attached to subdomains A and B1.

From: Chapter 13, Genome Replication

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.