Table 86.4Representative Local Control Rates and Survival for Patients with Squamous Cell Carcinoma of Common Head and Neck Sites Treated with Definitive Radiotherapy

Stage by siteLocal control (%)Survival* (%)
Oral cavity
Oral tongue
T180–9075–80
T260–8540–60
T330–5020–30
T424–4510–15
Floor of mouth
T175–8570–85
T260–8050–60
T330–5015–40
T45–305–20
Oropharynx
Base of tongue
T180–9565–85
T260–7540–55
T340–6515–20
T430–505–20
Tonsil/tonsillar fossa
T175–9565–85
T260–8055–60
T335–7020–40
T420–3010–15
Soft palate
T190–10090–95
T275–8565–75
T360–7030–40
T425–3510–15
Nasopharynx
T170–8560–75
T250–6050–65
T320–4525–50
T415–355–30
Hypopharynx
Pyriform sinus
T160–7030–50
T240–5020–45
T330–4015–25
T410–255–20
Larynx
Supraglottic
T180–9065–90
T260–8050–65
T335–7035–55
T430–6015–40
Glottis
T185–9580–95
T265–7560–85
T320–3535–60
T415–3010–30

Local control is for radiation alone. Survival data include surgical salvage for radiation failures. Overlap in the two sets of figures is due to data coming from different patient series, which are a heterogeneous mix of nodal stages, Kmofsky scores, tumor differentiation.

*

Adapted from Laramore.157

From: Chapter 86, Head and Neck Cancer

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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