Table 148.3Types of Renal Injury Caused by Cancer Chemotherapeutic Agents

Pathologic FindingCausative Agent
Acute glomerulonephritisNone reported
Acute tubular necrosisPlicamycin
Cisplatin (?)
Interstitial nephritisNitrosoureas
Membranous glomerulonephritisGallium nitrate (?)
(protein-losing)AZQ (diaziquone)
Obstructive uropathyMethotrexate (?)
Renal tubular acidosis5-Azacytidine
Renal vasculitisMitomycin C

From: Chapter 148, Urologic Complications

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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