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Bast RC Jr, Kufe DW, Pollock RE, et al., editors. Holland-Frei Cancer Medicine. 5th edition. Hamilton (ON): BC Decker; 2000.
Table 54.1Relative Potencies and Equivalent Dose of Corticosteroids
| Compound | Relative Anti-inflammatory potency | Relative Sodium-Retaining Potency | Duration of Action* | Approximate Equivalent Dose † (mg) |
|---|---|---|---|---|
| Cortisol | 1 | 1 | S | 20 |
| Cortisone | 0.8 | 0.8 | S | 25 |
| Corticosterone | 0.4 | 15 | S | — |
| Fludrocortisone | 10 | 125 | S | — |
| Prednisone | 4 | 0.8 | I | 5 |
| Prednisolone | 4 | 0.8 | I | 5 |
| 6a-methylprednisolone | 5 | 0.5 | I | 4 |
| Triamcinolone | 5 | 0 | I | 4 |
| Paramethasone | 10 | 0 | L | 2 |
| Betamethasone | 25 | 0 | L | 0.75 |
| Dexamethasone | 25 | 0 | L | 0.75 |
| Deoxycorticosterone | 0.2 | 100 | — | — |
| Aldosterone | 0.3 | 3000 | — | — |
- *
S = short or 8- to 12-h biologic half-life; I = intermediate or 12- to 36-h biologic half-life; L = long or 36- 72-h biologic half-life (see Rose and Saccar 230).
- †
These dose relationships apply only to oral or intravenous administration; relative potencies may differ greatly when injected intramuscularly or into joint spaces. From Haynes and Murad.229
- Table 54.1, Relative Potencies and Equivalent Dose of Corticosteroids - Holland-...Table 54.1, Relative Potencies and Equivalent Dose of Corticosteroids - Holland-Frei Cancer Medicine
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