Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 85.12Clinical Features of Primary Hyperparathyroidism due to Parathyroid Carcinoma and Benign Tumors
| Cancer* | Benign† | |
|---|---|---|
| Incidence | 2–4% | 96–98% |
| Female:male | 1:1 | 3:1 |
| Age (yr) | ||
| Mean | 45 | 58 |
| Range | 12–84 | 17–83 |
| Palpable neck mass | 42% | Rare |
| Serum calcium | ||
| Mean mg/dL (mmol/L) | 15 (3.75) | 11–12 (2.75–3.0) |
| >14 mg/dL (3.5 mmol/L) | 64% | <10% |
| Renal disease | 56% | 20% |
| Lithiasis | 49% | 20% |
| Nephrocalcinosis | 23% | Rare |
| Decreased function | 51% | 14% |
| Bone disease | 63% | 6% |
| Osteitis fibrosa cystica | 36% | 4% |
| Renal and bone disease | 39% | Rare |
| Gastrointestinal disease | ||
| Peptic ulcer | 11% | 8% |
| Pancreatitis | 11% | Rare |
| Asymptomatic | 3% | 47% |
- *
From references 417, 418, 481, and 490.
- †
From references 442, 444, 445, 447, 482.