Table 16.6Results of Long-term Carcinogenicity Bioassays of Sprague-Dawley Rats Injected Into the Peritoneal Cavity with Various Asbestos Minerals

Test MaterialNo. of AnimalsNo. of Animals Bearing Peritoneal Mesotheliomas
Amosite4036
Anthophyllite4033
Chrysotile (California)4029
Chrysotile (Canada)4032
Chrysotile (Rhodesia)4033
Crocidolite4039
H2O (controls)1500

A single injection of 25 mg in H2O was used.

From Maltoni and Minardi. 21 Reproduced by permission.

From: Chapter 16, Physical Carcinogens

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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