Table 16.6Results of Long-term Carcinogenicity Bioassays of Sprague-Dawley Rats Injected Into the Peritoneal Cavity with Various Asbestos Minerals

Test MaterialNo. of AnimalsNo. of Animals Bearing Peritoneal Mesotheliomas
Chrysotile (California)4029
Chrysotile (Canada)4032
Chrysotile (Rhodesia)4033
H2O (controls)1500

A single injection of 25 mg in H2O was used.

From Maltoni and Minardi. 21 Reproduced by permission.

From: Chapter 16, Physical Carcinogens

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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