FIGURE 7.5. Experience-dependent plasticity of cortical visual activities.

FIGURE 7.5

Experience-dependent plasticity of cortical visual activities. (A) Fluorescence responses elicited by LED light stimuli in the visual cortex after monocular deprivation (MD) of the right eye. Nondeprived eye responses in the binocular zone (a) and monocular zone (b), and deprived eye responses in the binocular zone (c) and monocular zone (d) are shown. These images were obtained from the same mouse. (B) Amplitudes of fluorescence responses (ΔF/F0) in the contralateral binocular zone, ipsilateral binocular zone and contralateral monocular zone. Means and S.E.M.s from 15 mice are shown. Statistical differences were evaluated by Mann Whitney U-test. (C) Fluorescence responses elicited by moving grating patterns 2 weeks after MD performed between P26 and P33. Nondeprived eye responses in the binocular zone (a) and the monocular zone (b), and deprived eye responses in the binocular zone (c) and the monocular zone (d) are shown. These images were obtained from the same mouse. Deprived eye responses were reduced after MD compared with nondeprived eye responses in the binocular zone, whereas those in the monocular zone were not. (D) Time course of fluorescence responses elicited by moving grating patterns in the contralateral (a) and ipsilateral (b) binocular zones, and contralateral monocular zone (c) of the visual cortex 2 weeks after MD, performed between P26 and P33. (Modified from Tohmi, M., Kitaura, H., Komagata, S., Kudoh, M., and Shibuki, K. 2006. J. Neurosci. 26: 11775–11785. With permission.)

From: Chapter 7, Flavoprotein Fluorescence Imaging of Experience-Dependent Cortical Plasticity in Rodents

Cover of In Vivo Optical Imaging of Brain Function
In Vivo Optical Imaging of Brain Function. 2nd edition.
Frostig RD, editor.
Boca Raton (FL): CRC Press/Taylor & Francis; 2009.
Copyright © 2009, Taylor & Francis Group, LLC.

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